A disease in which defective metabolism of uric acid causes arthritis, especially in the smaller bones of the feet, deposition of chalkstones, and episodes of acute pain. Pain and inflammation occur when too much uric acid crystallizes and deposits in the joints. Symptoms of gout include severe pain, redness, and swelling in joints, often the big toe. Attacks can come suddenly, often at night. Source: Dr. John Axe.
